Would that be especially useful?
Let's say I have two users valid: "sextant" and "NorelcoShaverFan" on my board, among 500 "spammy" registrants. It seems to me it would be a very bad user interface to present the user with a list of 502 users matching a wide swath of wildcards. And we already have wildcard-based pruning, so an admin could enter *viagra* and see who matches that.
However, I would see the utility in the following:
Admin enters *sex* in the "prune users matching this username" box. Admin sees the listing of matching users, showing certain statistics, like post count, number of posts in the queue, website URL, whatever. He can then remove certain users from the pruning list. So now he could prune *sex* and protect "sextant" from being pruned. (this user just likes circumnavigating the globe
). This would be a decent improvement on the current functionality, which is useless if there are legitimate users matching some wildcard.